학술논문
Lethal Capecitabine Toxicity in Patients With Complete Dihydropyrimidine Dehydrogenase Deficiency Due to Ultra-Rare DPYD Variants.
Document Type
Article
Author
van Kuilenburg, André B.P.; Pleunis-van Empel, Marjolein C.H.; Brouwer, Rick B.; Sijben, Angelique E.J.; Knapen, Daan G.; Oude Munnink, Thijs H.; van Zanden, Jelmer J.; Janssens-Puister, Jenny; Dobritzsch, Doreen; Meinsma, Rutger; Meijer-Jansen, Judith; van Dooren, Silvy J.M.; Vijzelaar, Raymon; Pop, Ana; Salomons, Gajja S.; Maring, Jan Gerard; Niezen-Koning, Klary E.
Source
Subject
*DIHYDROPYRIMIDINE dehydrogenase
*GLUCOSE-6-phosphate dehydrogenase deficiency
*
Language
ISSN
2473-4284
Abstract
A DPD deficiency should be considered in case of severe toxicity even in the absence of common risk variants in DPYD. [ABSTRACT FROM AUTHOR]