학술논문
Treatment of spasticity in a spinal cord-injured patient with intrathecal morphine due to intrathecal baclofen tolerance - a case report and review of literature.
Document Type
Article
Author
Source
Subject
*SPASTICITY
*SPINAL cord injuries
*MORPHINE
*DRUG tolerance
*PARAPLEGIA
*
*
*
*
Language
ISSN
1362-4393
Abstract
STUDY DESIGN:: Case report. OBJECTIVE:: To report treatment of spasticity in a spinal cord-injured person with intrathecal morphine after the person developed tolerance to intrathecal baclofen. METHOD:: Spasticity in a 36-year-old man with T6 complete paraplegia was treated with increasing doses of intrathecal baclofen. When he developed tolerance to intrathecal baclofen, he was given continuous infusion of morphine intrathecally. SETTING:: Regional Spinal Injuries Centre, UK. RESULTS:: Spasticity was adequately controlled by intrathecal morphine. CONCLUSION:: In spinal cord-injured patients with severe spasticity, who become tolerant to intrathecal baclofen, treatment with intrathecal morphine may be useful.Spinal Cord (2003) 41, 586-589. doi:10.1038/sj.sc.3101471 [ABSTRACT FROM AUTHOR]