학술논문

Transient nephrogenic diabetes insipidus caused by fetal exposure to haloperidol.
Document Type
Article
Source
Renal Failure. Jul2014, Vol. 36 Issue 6, p951-952. 2p.
Subject
*HALOPERIDOL
*MENTAL illness treatment
*DRUG dosage
*DIABETES insipidus
*NEONATAL diseases
*PREGNANCY complications
*DEHYDRATION
*THERAPEUTICS
RISK factors
Language
ISSN
0886-022X
Abstract
Haloperidol is commonly used in the treatment of psychiatric disorders. Data from animal experiments indicate haloperidol is not teratogenic, but is embryotoxic in high doses. For the first time, we report a neonate with transient nephrogenic diabetes insipidus (DI) caused by fetal exposure to haloperidol. The magnitude of risk associated with the use of haloperidol during pregnancy appears to be small, but nephrogenic DI secondary to haloperidol is a serious condition with the risk of hypernatremic dehydration. Haloperidol can have adverse effects on the fetus and newborn infant, that's why one should prevent the use of haloperidol during pregnancy and lactation. [ABSTRACT FROM AUTHOR]