학술논문
Chronic neutropenic colitis with complete colonic obstruction in a patient with severe congenital neutropenia associated with G6PC3 mutations.
Document Type
Article
Author
Source
Subject
*ISCHEMIC colitis
*COLITIS
*NEUTROPENIA
*INGUINAL hernia
*GRANULOCYTE-colony stimulating factor
*INFLAMMATORY bowel diseases
*CROHN'S disease
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Language
ISSN
0939-5555
Abstract
Dear Editor, Severe congenital neutropenia (SCN) is a heterogeneous group of rare inherited bone marrow failure syndromes characterized by absolute neutrophil count (ANC) lower than 0.5 × 10 SP 9 sp /L, increased susceptibility to bacterial infections, and high propensity to leukemic transformation [[1]]. Manifestations from the digestive system have been rarely reported in I G6PC3- i SCN patients and include inflammatory bowel disease (IBD), most closely resembling Crohn's disease, and IBD-like chronic inflammation of the large bowel [[7]]. [Extracted from the article]