부산대학교 도서관

Oxidative phosphorylation is an efficient way to generate the cellular energy currency ATP in a cascade of redox reactions, which ultimately terminate in the reduction of molecular oxygen to water. Interestingly, both excess and deficiency of oxygen can induce oxidative distress, therefore, maintaining oxygen homeostasis is an important factor to ensure proper cellular function. Different tissues in the human body are physiologically exposed to different partial pressures of oxygen, therefore "normoxia" needs to be seen in a cell type-specific context, which is defined as providing an optimal condition for the physiology of this special cell or tissue. [Extracted from the article]