학술논문

Optical Coherence Tomography Angiography Findings of Iris Ischemia and Reperfusion in Cytomegalovirus Panuveitis.
Document Type
Case Study
Source
Ocular Immunology & Inflammation. Oct/Nov2022, Vol. 30 Issue 7/8, p1595-1598. 4p.
Subject
*OPTICAL coherence tomography
*IRIS (Eye)
*FLUORESCENCE angiography
*ANGIOGRAPHY
*REPERFUSION
*IMMUNE reconstitution inflammatory syndrome
*IRIS (Eye) diseases
Language
ISSN
0927-3948
Abstract
To report a case of iris ischemia in an eye affected by Cytomegalovirus (CMV)-related Chronic Retinal Necrosis (CRN) with partial reperfusion after antiviral therapy demonstrated by optical coherence tomography angiography (OCTA). Retrospective case report. Multimodal imaging was performed at each follow-up visits. At baseline, the clinical findings and PCR on aqueous confirmed the diagnosis of CMV-induced CRN, while OCTA and Fluorescein Angiography showed multi-sectoral retinal and iris non-perfusion. After three weekly intravitreal injections of Foscarnet and retinal photocoagulation, the clinical and angiographic picture improved, with partial reperfusion of both retinal and iris vasculature. Retinal and iris non-perfusion in CRN can be partially reversible, if prompt treatment is administered. OCTA of the anterior segment allowed an accurate follow-up of the iris vasculature and its perfusion. [ABSTRACT FROM AUTHOR]