학술논문
Synthesis and Structural Characterization of Novel 2-Aminomethyl Quinazolin4(3H)-ones as Organic Building Blocks.
Document Type
Article
Author
Source
Subject
*QUINAZOLINONES
*ORGANIC chemistry
*QUINAZOLINE
*PHARMACEUTICAL chemistry
*NUCLEAR magnetic resonance spectroscopy
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Language
ISSN
1301-4048
Abstract
Quinazoline and quinazolinone derivatives display an extensive application in organic and pharmaceutical chemistry, and they have been used as natural and synthetic materials for medicinal chemistry purposes. Here I reported an investigation of a new series of quinazolinone ring derivatives. In this context, starting from the methyl anthranilate, six quinazolinone derivatives (4a-f) with various aminomethyl moieties at position 2 were synthesized (89-80%). The structures of compounds 4a-f were identified using FTIR and NMR Spectroscopy (¹H NMR - 13C NMR). The data obtained from the all spectra clearly identify the structures of the compounds. [ABSTRACT FROM AUTHOR]