학술논문

Fluorene-Based Multicomponent Reactions.
Document Type
Article
Source
Synlett. 2022, Vol. 33 Issue 2, p155-160. 6p.
Subject
*FLUORENONE
*FLUORENE
*MATERIALS science
*SPIRO compounds
*SCIENTIFIC discoveries
Language
ISSN
0936-5214
Abstract
Fluorene and fluorenone are privileged structures with extensive utility in both materials science and drug discovery. Here, we describe syntheses of those moieties through isocyanide-based multicomponent reactions (IMCRs) and the incorporation of the products in diverse and complex derivatives that can be further utilized. We performed six different IMCRs, based on the dual functionality of 9-isocyano-9 H -fluorene, and we describe 23 unprecedented adducts. [ABSTRACT FROM AUTHOR]