학술논문
Levosimendan in Two Neonates with Ischemic Heart Failure and Pulmonary Hypertension.
Document Type
Article
Author
Source
Subject
*PEDIATRIC pharmacology
*HEART failure in children
*PERSISTENT fetal circulation syndrome
*PULMONARY hypertension
*ISCHEMIA
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Language
ISSN
1661-7800
Abstract
We report the successful and safe use of levosimendan, a new calcium-sensitizing agent with positive inotropic and vasodilatory action, in 2 critically ill term newborns with acute heart failure and pulmonary hypertension in the absence of any underlying heart malformation and/or previous cardiosurgical procedures. During the neonatal period, levosimendan may represent an ideal drug for immature myocardium characterized by a higher calcium-dependent contractility than in adults. Copyright © 2011 S. Karger AG, Basel [ABSTRACT FROM AUTHOR]