학술논문
Identification of the bacterial etiology of culture-negative endocarditis by amplification and sequencing of a small ribosomal RNA gene
Document Type
Article
Author
Source
Subject
*ETIOLOGY of diseases
*ENDOCARDITIS
*
Language
ISSN
0732-8893
Abstract
We report two cases of culture-negative bacterial endocarditis in which the organisms were identified by amplification and sequencing of the bacterial 16S rRNA gene. These results support an important role for polymerase chain reaction followed by direct sequencing to determine the etiology of culture-negative bacterial endocarditis and to guide appropriate antimicrobial therapy. [Copyright &y& Elsevier]