학술논문

Epstein-Barr virus infection resembling autoimmune hepatitis with lactate dehydrogenase and alkaline phosphatase anomaly.
Document Type
Journal Article
Source
Journal of Gastroenterology. 1999, Vol. 34 Issue 6, p706-712. 7p.
Subject
*EPSTEIN-Barr virus diseases
*CHRONIC active hepatitis
*LIVER diseases
*AUTOIMMUNE diseases
Language
ISSN
0944-1174
Abstract
A 73-year-old man had fever, lymphadenopathy, granulocytopenia, thrombocytopenia, ascites, pleural effusion, liver injury, and an allergic-like skin rash. Autoantibodies, such as anti-nuclear antibody, were shown, and there were lactate dehydrogenase and alkaline phosphatase anomalies and platelet-associated IgG. His liver injury resembled that in autoimmune hepatitis. He was diagnosed with Epstein-Barr virus (EBV) infection associated with autoimmunization because of his clinical course, fluctuation of anti EBV antibodies and positive EBV genome in circulating lymphocytes and serum. This case suggests a close relationship between EBV infection and autoimmunization or autoimmune-like hepatitis. [ABSTRACT FROM AUTHOR]