학술논문

Serum interleukin-5 levels correlate with disease activity of Churg–Strauss syndrome in a patient treated with a leucotriene receptor antagonist, pranlukast, and inhaled corticosteroid.
Document Type
Article
Source
Scandinavian Journal of Rheumatology. Aug2010, Vol. 39 Issue 4, p341-343. 3p. 1 Color Photograph, 1 Chart.
Subject
*INTERLEUKIN-5
*CASE studies
*EOSINOPHILS
*BASIC proteins
*CHURG-Strauss syndrome
*CORTICOSTEROIDS
Language
ISSN
0300-9742
Abstract
This case report demonstrates that interleukin (IL)-5 levels and eosinophil cationic protein (ECP) correlated well with disease activity of Churg–Strauss syndrome (CSS) in a patient receiving treatment with leucotriene receptor antagonist and inhaled corticosteroid. In addition, ECP was localized in the inflamed tissue. IL-5 levels may thus provide a clue to therapeutic efficacy in patients with CSS using leucotriene receptor antagonists and inhaled corticosteroid. [ABSTRACT FROM AUTHOR]