부산대학교 도서관

[17] The results reported that the ligand with an isopropyl group on the oxazoline stereocentre led to an I ee i of 9% after 4 h while the ligand bearing a phenyl group at the same position led to a 16% I ee i , after 72 h. Keywords: nitriles; S N Ar alkylation; Grignard reaction; pyridine oxazoline; zinc chloride EN nitriles S N Ar alkylation Grignard reaction pyridine oxazoline zinc chloride 1834 1838 5 08/29/23 20230915 NES 230915 Graph Central to asymmetric catalysis using metal complexes is the design and development of chiral ligands with novel steric and electronic properties. [6] These sites are chosen due to the observation that alterations to the pyridine ring primarily contributes to the ligand's electronic effects while changing the substituent on the oxazoline ring mainly impacts the ligand's steric factors. Nitriles, S N Ar alkylation, Grignard reaction, pyridine oxazoline, zinc chloride. [Extracted from the article]