학술논문

PROPRANOLOL IN THE TREATMENT OF SUBGLOTTIC HAEMANGIOMA.
Document Type
Article
Source
Pedijatrija Danas: Pediatrics Today. 2014, Vol. 10 Issue 2, p159-162. 4p.
Subject
*PROPRANOLOL
*HEMANGIOMAS
*DYSPNEA
*TACHYCARDIA
*STENOSIS
*DRUG dosage
*THERAPEUTICS
Language
ISSN
1840-0914
Abstract
Objective -- Subglottic infantile haemangioma (SGH) is a rare but potentially life-threatening disease. We describe a case of successful treatment with propranolol of a severely respiratory compromised 2-month-old infant with an obstructing SGH. Case report -- A fullterm 2-month-old male infant, weighing 4.8 kg, without cutaneous haemangioma, presented with stridor, dyspnoea, oxygen desaturation and tachycardia. Contrast enhanced neck--chest CT scan was used to diagnose a 5x7x7 mm subglottic elliptic lesion, referable to SGH with a free air column of 2 mm wide. Per oral propranolol was started with a therapeutic dosage of 2 mg/kg/day in 3 administrations. On the second day of treatment there was rapid clinical improvement of the infant with withdrawal of respiratory symptoms. After treatment, the control CT showed the regression of SGH. Twenty-one months later the patient is without respiratory symptoms. Conclusion -- Propranolol medical treatment should be considered in all subglottic haemangioma, even in acute cases. [ABSTRACT FROM AUTHOR]