학술논문
Dietary calcium and vitamin D intakes in childhood and throughout adulthood and mammographic density in a British birth cohort.
Document Type
Journal Article
Author
Source
Subject
*DIETARY calcium
*VITAMIN D in human nutrition
*BREAST exams
*BREAST cancer
*MAMMOGRAMS
*MENOPAUSE
*DIET
*COMPARATIVE studies
*LONGITUDINAL method
*RESEARCH methodology
*MEDICAL cooperation
*RESEARCH
*RESEARCH funding
*VITAMIN D
*EVALUATION research
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Language
ISSN
0007-0920
Abstract
We examined the role of dietary calcium and vitamin D intakes in childhood and throughout adulthood in relation to mammographic density using data from a nationally representative cohort of 1161 women followed up since their birth in 1946. Dietary intakes at the age of 4 years were determined by 24-h recalls and at the ages of 36, 43 and 53 years by 5-day food records. After adjusting for known risk factors and confounders, no evidence of a relationship between dietary calcium or vitamin D intakes and mammographic density approximately at the age of 50 years was found, except for a cross-sectional relationship between dietary calcium intake at the age of 53 years and breast density in women who were post-menopausal at the time of mammography, with those in the top fifth of the distribution of calcium intake having a 0.53 s.d. lower percent breast density than those in the lowest fifth (P-value <0.01 for linear trend). [ABSTRACT FROM AUTHOR]