부산대학교 도서관

This article explores the role of AU-binding factor 1 (AUF-1) in chronic inflammatory skin conditions such as atopic dermatitis (AD) and psoriasis. The study examines the expression of AUF-1 in skin biopsies of AD and psoriasis patients and investigates the modulation of AUF-1 in vitro using human keratinocyte cell cultures. The results show a different pattern of AUF-1 expression in AD compared to psoriasis, suggesting a potential role of AUF-1 in chronic immune-driven skin inflammation. The findings highlight the importance of understanding endogenous mechanisms involved in resolving AD and identifying new therapeutic targets. [Extracted from the article]