학술논문
Vox Sanguinis International Forum on typing and matching strategies in patients on anti‐CD38 monoclonal therapy: summary.
Document Type
Article
Author
Source
Subject
*IMMUNOGLOBULINS
*MONOCLONAL antibodies
*BLOOD transfusion
*BLOOD proteins
*BLOOD platelets
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Language
ISSN
0042-9007
Abstract
The article reports that the immunotherapeutic strategies are emerging as novel therapeutic approaches in multiple myeloma with several monoclonal antibodies being in advanced stages of clinical development. CD38 targeting antibodies are promising and some of them are in the market in many countries. Therapeutic CD38-targeting antibodies were shown to interfere with pretransfusion laboratory tests due to weak expression of CD38 on human erythrocytes.