학술논문

Fingolimod effect on brain volume loss independently contributes to its effect on disability.
Document Type
Article
Source
Multiple Sclerosis Journal. Jun2015, Vol. 21 Issue 7, p916-924. 9p. 3 Charts, 1 Graph.
Subject
*FINGOLIMOD
*DISEASE progression
*MAGNETIC resonance imaging of the brain
*MULTIPLE sclerosis
*DISEASE relapse
*PATIENTS
Language
ISSN
1352-4585
Abstract
The article presents a study which investigates whether the impact of fingolimod on disability progression was caused by its effects on brain volume loss and magnetic resonance imaging (MRI) lesions. The study assessed brain volume change and the effect of fingolimod therapy on disability progression in patients with multiple sclerosis (MS). The study found that the effect of fingolimod treatment on brain volume loss and relapses were both predictors of the treatment's impact on disability.