학술논문
Donor Unrestricted T Cells: Linking innate and adaptive immunity.
Document Type
Article
Source
Subject
*T cells
*NATURAL immunity
*ANTIGEN presentation
*B cells
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*
*
Language
ISSN
0264-410X
Abstract
Donor Unrestricted T Cells (DURTs) are characterized by their use of antigen presentation molecules that are often invariant. As these cells recognize diverse mycobacterial antigens, often found in BCG, these cells have the potential to either serve as targets for vaccination, or as a means to enable the induction of traditional T and B cell immunity. Here, we will review specific DURT family members, and their relationship to BCG. [ABSTRACT FROM AUTHOR]