학술논문
Self-reported gastrointestinal symptoms are more common in liver transplanted transthyretin amyloidosis patients than in healthy controls and in patients transplanted for end-stage liver disease.
Document Type
Letter
Source
Subject
*LIVER transplantation
*LIVER diseases
*CARDIAC amyloidosis
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Language
ISSN
1350-6129
Abstract
Highlights from the article: Gastrointestinal (GI) complications are common in hereditary transthyretin (TTR) amyloid (ATTRm) amyloidosis, and previous studies indicate that the symptoms tend to increase after liver transplantation [[1]]. The prevalence of GI symptoms was higher in ATTRm patients than in healthy controls but equal to that of transplanted controls and, among patients, abdominal pain, bloating and diarrhoea were the most common symptoms, whereas constipation and satiety were the symptoms with the highest proportion of patients reporting severe or very severe discomfort (Table 1).
| Symptom cluster | ATTRm patients ( | LTx controls ( | Healthy controls ( | ||
| Any GI symptom | 95% | 94% | . |