부산대학교 도서관

Inflammatory disorders and auto-inflammatory diseases are multifaceted ailments marked by dysregulated immune responses and chronic inflammation. Understanding the pathophysiology of these disorders and creating successful treatment techniques are major areas of research and clinical interest. This review article gives an updated summary of the pathophysiology of inflammatory illnesses and auto-inflammatory diseases, as well as current therapeutic techniques. These diseases are caused by a complex interaction of genetic predisposition, environmental stimuli, and immune system dysregulation. Abnormal cytokine signaling, immune cell malfunction, and tissue damage induced by chronic inflammation are all important mechanisms. Insights into the pathogenic processes that underpin disease have paved the way for the development of specific treatment approaches. Nonsteroidal anti-inflammatory medications (NSAIDs), corticosteroids, biologic therapy, targeted therapies, and immunomodulatory therapies are all used to treat inflammatory disorders and auto-inflammatory diseases. Traditional treatments alleviate symptoms, whereas newer biologic and targeted medications selectively target immune system components to control the inflammatory response. Immunomodulatory medicines attempt to rebalance the immune system and control abnormal immunological activity. This review focuses on the most recent developments in treatment techniques, such as the use of biologics that target specific cytokines and cellular pathways, as well as targeted therapies that target key molecular targets implicated in inflammation and autoimmune. Furthermore, the ability of immunomodulatory medicines to modify immune response is explored. [ABSTRACT FROM AUTHOR]