학술논문

Prolonged and mixed non-O157 Escherichia coli infection in an Australian household.
Document Type
Article
Source
Clinical Microbiology & Infection. May2012, Vol. 18 Issue 5, pE140-E143. 4p.
Subject
*ENTEROBACTERIACEAE
*GRAM-negative bacterial diseases
*ESCHERICHIA coli
*PUBLIC health
*MOLECULAR epidemiology
Language
ISSN
1198-743X
Abstract
Clin Microbiol Infect 2012; 18: E140-E143 Abstract An Australian family was identified through a Public Health follow up on a Shiga-toxigenic Escherichia coli (STEC) positive bloody diarrhoea case, with three of the four family members experiencing either symptomatic or asymptomatic STEC shedding. Bacterial isolates were submitted to stx sequence sub-typing, multi-locus variable number tandem repeat analysis (MLVA), multi-locus sequence typing (MLST) and binary typing. The analysis revealed that there were multiple strains of STEC being shed by the family members, with similar virulence gene profiles and the same serogroup but differing in their MLVA and MLST profiles. This study illustrates the potentially complicated nature of non-O157 STEC infections and the importance of molecular epidemiology in understanding disease clusters. [ABSTRACT FROM AUTHOR]