부산대학교 도서관

Aim: To evaluate the change in central macular thickness and to determine the incidence of cystoids macular edema (CME) in postkeratoplasty patients with Optical Coherence Tomography (OCT). Introduction: CME is a known complication of ocular surgery. The postoperative visual outcome of keratoplasty patients is governed by various factors like astigmatism, graft clarity, cystoid macular edema, and postoperative glaucoma. With evolution of Optical coherence tomography topographic evaluation of retina is possible up to 10-μm axial resolution Method: A prospective study included 23 eyes, out of which 20 eyes underwent penetrating keratoplasty (PK) and 3eyes underwent Descemet's Stripping Endothelial Keratoplasty (DSEK). Postoperative central Macular Thickness (CMT) analysis was done with OCT at 1, 2 and 3 month interval. CMT > 250u, loss of foveal contour and presence of cystoids space over macula were considered as Cystoid Macular Edema (CME). Results and conclusion: Incidence of CME after 1month of PK was 30%, 20% at 2 month and 10% at 3 month. One out of 4 DSEK patient developed CME. In PK group, change in CMT between 1 and 2 month was significant (p value 0.03) but there was no statistically significant difference after 2month (p value 0.38). In DSEK group, at 1 month interval there was no statistically significant difference in CMT change (p value 0.66 and 0.33P). There was no statistically significant difference found in age matched patients of Pseudophakic bullous keratopathy compared from PK and DSEK group. Higher CMT at 1, 2 and 3 month in post triple procedure but it was not significant in comparison to other PK cases. There was a significant change in CMT between 1 month and 2 month post PK surgery, but not beyond that. CMT change in uncomplicated post Triple Surgery is same as post PK. There was no significant change in CMT in DSEK group.CMT change in PK is also related to indication of surgery. No direct relation between visual acuity and CME [ABSTRACT FROM AUTHOR]