부산대학교 도서관

Introduction: Sodium levels should be between 135 and 145mEq/L. A cell's ability to maintain homeostasis is necessary for proper operation. An imbalance in the body's general water control may be the cause of abnormal sodium levels. High sodium levels caused by irregular water balance are present in chronic liver illness that is not yet fully reversible. Aims: To assess the correlation among serum sodium imbalance and prognosis in decompensated liver disease patients and its clinical relevance. Materials and Methods: It was a prospective hospital based observational study of 75 patients with biochemical and clinical evidence of chronic liver disease (CLD), who were admitted in the medical ward of Katihar Medical College, Katihar, since December 2020 to May 2022. Result: In present study, 69 (92%) patients were alcoholic, 1 (1.33%) had HCV, 5 (6.67%) had HBV, and none had primary biliary cirrhosis, cryptogenic cirrhosis, and autoimmune hepatitis. There was abdominal distension in 75 patients (100%), jaundice in 22 (29.33%), lower limb swelling in 75 (100%), GI bleed in 19 (25.33%), and altered sensorium in 15 patients (20%). Conclusion: It has been shown that low serum sodium is a poor prognostic marker and increases the risk of early mortality. The few available treatments for hyponatremia currently consist of appropriate free water restriction, stopping diuretics, and may be short-term vaptan (eg; Tolvaptan) usage. [ABSTRACT FROM AUTHOR]