학술논문
Origin of Aymaras from Bolivia and their relationship with other Amerindians according to HLA genes.
Document Type
Article
Author
Source
Subject
*HLA histocompatibility antigens
*GENES
*POPULATION genetics
*POPULATION
*CHROMOSOMES
*CELL nuclei
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*
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Language
ISSN
0001-2815
Abstract
Aymara Amerindians from the Titicaca Lake Andean highlands are studied for HLA-A, HLA-B, HLA-DRB1 and HLA-DQB1 gene frequencies. Genetic distances, neighbour-joining and correspondence analyses are performed by using other Amerindian and worldwide populations (15384 chromosomes are studied). The HLA genetic profile of Aymaras is different from neighbouring and language-related Quechuas (Incas). Both Quechuas and Aymaras seem to present an HLA-DRB1*0901 high frequency, which is present in a very low frequency or absent in Mesoamericans (Mazatecans, Mayans) and most studied Amerindians. Moreover, it is observed a closer relatedness of Aymaras with Amerindians from the Amazon Basin and Chaco lowlands, compared to Quechuans. [ABSTRACT FROM AUTHOR]