학술논문

DNA binding and 3'-5' exonuclease activity in the murine alternatively-spliced p53 protein.
Document Type
Article
Source
Oncogene. 8/1/2002, Vol. 21 Issue 33, p5117. 10p. 5 Black and White Photographs, 1 Chart.
Subject
*TUMOR suppressor genes
*CANCER
*DNA
Language
ISSN
0950-9232
Abstract
Presents a study that examined the binding properties and exonuclease activity of tumor suppressor protein alternative spliced p53 (AS-p53). Background on the link between the tumor suppressor gene p53 and human cancer; Details on the binding of AS-p53 to natural and modified DNA targets; Discussion on the cellular role of AS-p53.