학술논문
A cure for AIDS: a matter of timing?
Document Type
Article
Author
Source
Subject
*AIDS treatment
*DRUG resistance
*ANTIVIRAL agents
*PHARMACOLOGY
*MAMMALS
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Language
ISSN
1742-4690
Abstract
Despite the huge clinical success of antiretroviral therapy, several factors such as side effects, requirement of life-long adherence, high cost, incomplete access to therapies and development of drug resistance make the quest for an ultimate cure of HIV/AIDS a worldwide priority of biomedical research. In this respect, several sterilizing or functional cures have been reported in the last years in both non-human primates and humans. This review provides a summary of the main results achieved so far, outlining their strengths as well as their limitations. A synthetic interpretation of these results could be pivotal in order to develop an effective and widely available cure. [ABSTRACT FROM AUTHOR]