학술논문

Determination of dexamethasone dose for cortisol suppression in adult common marmosets (Callithrix jacchus).
Document Type
Article
Source
Journal of Medical Primatology. Dec2022, Vol. 51 Issue 6, p407-410. 4p.
Subject
*CALLITHRIX jacchus
*DEXAMETHASONE
*MARMOSETS
*HYDROCORTISONE
*ADULTS
Language
ISSN
0047-2565
Abstract
We conducted a dose–response study of dexamethasone to investigate an optimal dexamethasone suppression test for common marmosets. Twelve marmosets received 0.1, 0.5, or 1.0 mg/kg dexamethasone. Doses of 0.5 and 1.0 mg/kg both suppressed endogenous cortisol for at least 18 h with greater individual variability in the lower 0.5 mg/kg dose. [ABSTRACT FROM AUTHOR]