부산대학교 도서관

Objectives: Henna is a small plant with therapeutic properties against bacterial infections including Staphylococcus aureus. The aqueous and alcoholic extracts of this plant can be used for the treatment of skin wounds. Eucalyptus is another plant with the same therapeutic properties, the ethanolic extracts of which can be used to treat many infectious and diseasescaused by methicillin susceptibility or Staphylococcus aureus resistance. Researchers have attempted to find new herbal combinationsto substituteantibiotics in orderto improvethesideeffects and reduce the costsof chemical drugs. Therefore, in this study, the antimicrobial effects of henna and Eucalyptus have been investigated on Staphylococcus aureus isolated from skin lesions. Materials and Methods: In this study, henna and Eucalyptusextracts wereobtained. The antimicrobial effects of aqueous and alcoholic extracts of henna were investigated on 45 Staphylococcus aureus isolates, resistant and susceptible to methicillin(15 resistant isolates and 30 susceptible isolates).Moreover,the antimicrobial effects of ethanolic extracts of Eucalyptus were tested on 15 isolates of Staphylococcus aureus resistant to methicillin, using disk diffusion method and measurement ofthe diameter of non-growth halo on Mueller-Hinton agar. Then, the minimum inhibitory concentrations of these two extracts weredetermined, using micro-dilution broth. Staphylococcus aureus isolates resistant and susceptible to methicillinwere separated from skin ulcers. Results: In this study,the aqueous extracts of henna had an average minimum inhibitory concentration of 7.2 mg/ml and the ethanolic extracts had a minimum inhibitory concentration of 9.2 mg/ml. The ethanolic extracts of Eucalyptus had a minimum inhibitory concentration of 0.08mg/ml. Conclusion: The results showed that henna and Eucalyptushaveantibacterial effects against Staphylococcus aureus isolates, particularly methicillin-resistant strains. Therefore, they can be used in the treatment of skin infections and wounds. It is hoped that these natural plants can promote the prevention and treatment of skin infections. [ABSTRACT FROM AUTHOR]