학술논문
Interaction between leukemic-cell VLA-4 and stromal fibronectin is a decisive factor for minimal residual disease of acute myelogenous leukemia.
Document Type
Article
Author
Source
Subject
*BONE marrow diseases
*DISEASE relapse
*DRUG therapy
*ACUTE myeloid leukemia
*PATIENTS
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Language
ISSN
1078-8956
Abstract
Cites that bone marrow minimal residual disease causes relapse after chemotherapy in patients with acute myelogenous leukemia. Inducement of the drug resistance by the attachment of very late antigen-4 (VLA-4) on leukemic cells; Resistance of VLA-4-positive cells to anoikis; Interaction between VLA-4 and fibronectin.