부산대학교 도서관

A 2D transmission line matrix model is used to study thermal transfer in living tissues exposed to laser energy. Damage size because of thermal coagulation in thermal treatment of benign prostate hyperplasia is determined quantitatively. Results show a quasilinear dependency of blood perfusion on temperature at the beginning of coagulation. Immediately thereafter, blood perfusion decreases considerably until it shuts down when the tissue under investigation has been coagulated. Increase in perfusion rate ( ω) leads to high values of t100, which is the time required to reach a primary zone temperature of about 100 °C, and reflects the increased cooling created by perfusion. The transmission line matrix numerical model predicts the coagulation damage contours; that way, it has a clinical interest in therapy as an aid for clinicians because damage cannot be easily measured within patients. Results are validated through comparison with other researches. Copyright © 2014 John Wiley & Sons, Ltd. [ABSTRACT FROM AUTHOR]