학술논문
Transcriptional profiling of whole blood: a rich source of immune biomarkers in cancer.
Document Type
Article
Author
Source
Subject
*IMMUNOTHERAPY
*GENETIC transcription
*BLOOD testing
*BIOMARKERS
*IMMUNE response
*CANCER treatment
*MESSENGER RNA
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Language
ISSN
2162-4011
Abstract
Immunotherapy is at the forefront of cancer treatment, and biomarkers are urgently needed to predict patient response to therapy. Recently, we discovered a 4-gene peripheral blood mRNA signature for prolonged survival in patients treated with tremelimumab. Peripheral blood mRNA is a readily accessible and under-utilized source of clinically relevant biomarkers. [ABSTRACT FROM PUBLISHER]