학술논문
Associations of sedentary time, physical activity, and fitness with muscle glucose uptake in adults with metabolic syndrome.
Document Type
Article
Author
Source
Subject
*SKELETAL muscle physiology
*GLUCOSE metabolism
*SEDENTARY lifestyles
*RESEARCH
*BODY composition
*CARBOHYDRATE metabolism
*CARDIOPULMONARY fitness
*BIOLOGICAL transport
*OXYGEN consumption
*BLOOD sugar
*ACCELEROMETERS
*THIGH
*PHYSICAL activity
*METABOLIC syndrome
*RESEARCH funding
*RADIOPHARMACEUTICALS
*POSITRON emission tomography
*STATISTICAL correlation
*ERGOMETRY
*DEOXY sugars
*INSULIN resistance
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Language
ISSN
0905-7188
Abstract
Objective: The objective of the study was to investigate the associations of sedentary time, physical activity, and cardiorespiratory fitness with skeletal muscle glucose uptake (GU). Methods: Sedentary time and physical activity were measured with accelerometers and VO2max with cycle ergometry in 44 sedentary adults with metabolic syndrome. Thigh muscle GU was determined with [18F]FDG‐PET imaging. Results: Sedentary time (β = −0.374), standing (β = 0.376), steps (β = 0.351), and VO2max (β = 0.598) were associated with muscle GU when adjusted for sex, age, and accelerometer wear time. Adjustment for body fat‐% turned all associations non‐significant. Conclusion: Body composition is a more important determinant of muscle GU in this population than sedentary time, physical activity, or fitness. [ABSTRACT FROM AUTHOR]