부산대학교 도서관

Objectives: To evaluate the safety and feasibility of left bundle branch area pacing (LBBAP) in patients with valvular interventions. Methods: Eighty‐four patients were included in this study. All patients underwent recent surgical or percutaneous valvular interventions. LBBAP was attempted in all patients. Implant success rates, peri‐ and postprocedure electrocardiogram, pacing parameters, and complications were assessed at implant, and during follow‐up. Results: LBBAP implantation was successful in 80/84 (95%) patients. Mean age was 74.1 ± 13.8 years and 56% patients were male. Prior valvular replacements included: percutaneous aortic (26), surgical aortic (36), combined surgical aortic plus mitral (6), MVR (10), tricuspid (1), and pulmonic (1). Average LVEF was 52.6 ± 11%. Majority of patients underwent LBBAP due to atrioventricular block (76%) and sinus node disease (13%). Total procedure duration was 74.1 ± 12.5 min and fluoroscopic duration was 9.7 ± 6.8 min. Pacing parameters were stable during follow‐up period of 10.0 ± 6.3 months. Pacing QRS duration was significantly narrower than baseline QRS duration (131.5 ± 31.4 ms vs. 114.3 ± 13.7 ms, p <.001, respectively). No acute complications were observed. Mean follow‐up was 10.0 ± 6.3 months (median: 8.4 months, min: 1 and max: 24 months). During follow‐up, there were three device infections and two patients had loss of LBBA capture within 1 month of implant. Conclusions: LBBAP is a feasible and safe pacing modality in patients with prior interventions for valvular heart disease. [ABSTRACT FROM AUTHOR]