학술논문
Is MRSA more virulent than MSSA?
Document Type
Editorial
Author
Source
Subject
*MICROBIAL virulence
*METHICILLIN resistance
*STAPHYLOCOCCUS aureus
*DRUG resistance in microorganisms
*PATHOGENIC bacteria
*ANTIBIOTICS
*PATHOGENIC microorganisms
*MEDICAL microbiology
*MEDICAL research
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Language
ISSN
1198-743X
Abstract
Numerous clinical studies have indicated, based on mortality rates, that methicillin-resistant Staphylococcus aureus (MRSA) strains are more virulent than methicillin-susceptible S. aureus (MSSA) strains. In contrast, quantitative laboratory examinations of the presence and magnitude of pathogenic mechanisms and virulence factors in strains of MRSA and MSSA have generated conflicting data. The most important reason for these conflicting results is probably the heterogeneic nature of the resistant population. A comparison of selected and congenic MRSA and MSSA sub-populations of the same strain is required to resolve this issue. [ABSTRACT FROM AUTHOR]