학술논문
Autochthonous Human Case of Seoul Virus Infection, the Netherlands.
Document Type
Journal Article
Author
Source
Subject
*DISEASE prevalence
*PUBLIC health
*HEMORRHAGIC fever
*LABORATORY rats
*MEDICAL care
*ANIMALS
*HANTAVIRUSES
*HEMORRHAGIC fever with renal syndrome
*RATS
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Language
ISSN
1080-6040
Abstract
Orthohantaviruses are a group of rodentborne viruses with a worldwide distribution. The orthohantavirus Seoul virus (SEOV) can cause hemorrhagic fever with renal syndrome in humans and is distributed worldwide, like its reservoir host, the rat. Cases of SEOV in wild and pet rats have been described in several countries, and human cases have been reported in the United Kingdom, France, Canada, and the United States. In the Netherlands, SEOV has previously been found in wild brown rats. We describe an autochthonous human case of SEOV infection in the Netherlands. This patient had nonspecific clinical symptoms of an orthohantavirus infection (gastrointestinal symptoms and distinct elevation of liver enzymes). Subsequent source investigation revealed 2 potential sources, the patient's feeder rats and a feeder rat farm. At both sources, a high prevalence of SEOV was found in the rats. The virus closely resembled the Cherwell and Turckheim SEOV strains that were previously found in Europe. [ABSTRACT FROM AUTHOR]