학술논문
Right Ventricular Longitudinal Strain Measure Independently Predict Chronic Heart Failure Mortality.
Document Type
Article
Author
Source
Subject
*HEART ventricle diseases
*CONFIDENCE intervals
*STATISTICAL correlation
*CREATININE
*ECHOCARDIOGRAPHY
*GLOMERULAR filtration rate
*RIGHT heart ventricle
*HEART beat
*HEART failure
*INFANTS
*PROGNOSIS
*T-test (Statistics)
*EVALUATION research
*CONTINUING education units
*INTER-observer reliability
*PROPORTIONAL hazards models
*RECEIVER operating characteristic curves
*DATA analysis software
*DESCRIPTIVE statistics
*KAPLAN-Meier estimator
*INTRACLASS correlation
RESEARCH evaluation
*
*
*
*
*
*
*
*
*
*
*
*
*
*
*
*
*
*
*
*
Language
ISSN
0742-2822
Abstract
The assessment of right ventricular (RV) function still remains a challenge. Two-dimensional (2D) speckle tracking has recently been proposed to evaluate right ventricular function by analyzing myocardial deformation. The aim of this study was to evaluate the role of 2D systolic strain measures of RV in predicting mortality in patients with chronic heart failure (HF). We enrolled 332 outpatients in a stable clinical condition and in conventional therapy. A right ventricular-focused four-chamber view was analyzed by 2D speckle tracking to evaluate the global longitudinal strain of RV (RV-GLS) and the strain of RV free wall (RV-fwLS). During a mean follow-up of 36 ± 26 months, 64 patients died. Both RV-GLS and RV-fwLS were associated with all-cause mortality in univariate (HR: 1.16; 95% CI: 1.10-1.23; P < 0.001; C-index: 0.72; and HR: 1.10; 95% CI: 1.06-1.15; P < 0.001; C-index: 0.68, respectively) as well as multivariate analysis (HR: 1.13; 95% CI: 1.05-1.21; P:0.001; C-index: 0.85; and HR: 1.07; 95% CI: 1.02-1.12; P:0.004; C-index: 0.84, respectively). In conclusion, our findings demonstrate the role of RV 2D strain measures to independently predict mortality. These data highlight the clinical usefulness of this echocardiographic approach in the daily management of HF outpatients. [ABSTRACT FROM AUTHOR]