학술논문

Evaluation of the RESIST ACINETO multiplex immunochromatographic assay for detection of OXA-23-like, OXA-40/58-like and NDM carbapenemase production in Acinetobacter baumannii.
Document Type
Article
Source
Journal of Antimicrobial Chemotherapy (JAC). Nov2023, Vol. 78 Issue 11, p2771-2774. 4p.
Subject
*ACINETOBACTER baumannii
*CARBAPENEMASE
*CARBAPENEM-resistant bacteria
*BIOLOGICAL assay
*RAPID diagnostic tests
Language
ISSN
0305-7453
Abstract
Development of an immunochromatographic lateral flow assay to rapidly detect OXA-23-, OXA-40-, OXA-58- and NDM-mediated carbapenem resistance determinants in Acinetobacter baumannii. The most prevalent acquired carbapenemases in I A. baumannii i are class D oxacillinases, including the OXA-23, OXA-40 and OXA-58 groups. Seventy-two of 106 isolates harboured I bla i SB OXA-23 sb (68%), 17 I bla i SB OXA-72 sb (16%), three I bla i SB OXA-58 sb and one I bla i SB OXA-40 sb , while three isolates carried two oxacillinase genes (two I bla i SB OXA-23 sb / I bla i SB OXA-58 sb and one I bla i SB OXA-23 sb / I bla i SB OXA-72 sb ). [Extracted from the article]