학술논문
Expression of the transcribed ultraconserved region 70 and the related long non‐coding RNA AC092652.2‐202 has prognostic value in Chronic Lymphocytic Leukaemia.
Document Type
Article
Author
Bomben, Riccardo; Roisman, Alejandro; D'Agaro, Tiziana; Castellano, Giancarlo; Baumann, Tycho; Delgado, Julio; López‐Guillermo, Armando; Zucchetto, Antonella; Dal‐Bo, Michele; Bravin, Vanessa; Slavutsky, Irma; Vlasova, Anna; Guigó, Roderic; Martin‐Subero, Jose I.; Chapaprieta, Vicente; Beekman, Renee; Martin‐García, David; Beà, Sílvia; Salaverria, Itziar; Aymerich, Marta
Source
Subject
*NON-coding RNA
Language
ISSN
0007-1048
Abstract
The article presents a study which explored the possible role of Transcribed Ultraconserved Region (T-UCR) in the pathogenesis of CLL. Topics include potential clinical value of the significantly modulated T-UCRs in two independent cohorts of chronic lymphocytic leukemia (CLL) patients, expression levels of uc.70 and uc.414 in the same cases studied by microarrays and in an independent series of CLL cases, and expression of uc.70-related transcripts using RNAseq data of CLL cases.