학술논문

The Caenorhabditis elegans protein SAS-5 forms large oligomeric assemblies critical for centriole formation.
Document Type
Article
Source
eLife. May2015, p1-25. 25p.
Subject
*STRUCTURAL analysis (Science)
*OLIGOMERS
Language
ISSN
2050-084X
Abstract
The article presents a study that combines biophysical and structural analysis to uncover the architecture of SAS-5 and examine its functional implications in vivo, with work revealing that two distinct self-associating domains are necessary to form higher-order oligomers of SAS-5.