학술논문

Cardiovascular recurrence of high-grade osteosarcoma presenting as atrial thrombosis and pulmonary embolism: A case report and review of the pediatric literature.
Document Type
Letter
Source
Pediatric Hematology & Oncology. May2019, Vol. 36 Issue 4, p244-251. 8p.
Subject
*LITERATURE reviews
*THROMBOSIS
*PULMONARY embolism
*ADJUVANT treatment of cancer
*OSTEOSARCOMA
Language
ISSN
0888-0018
Abstract
In the era of neoadjuvant and adjuvant chemotherapy, extrapulmonary involvement by high-grade osteosarcoma (HGOS) is rare. Importantly however, HGOS metastasis in the form of cardiovascular tumor thrombus portends a dismal prognosis. Thus, prompt and accurate identification of tumor thrombus is crucial. We report here two unique cases of recurrent HGOS, presenting as thrombotic events, in order to increase awareness and index of suspicion among practitioners regarding this presentation. Additionally, we review 14 previously reported pediatric cases of cardiovascular metastatic HGOS. [ABSTRACT FROM AUTHOR]