학술논문

Malaria-induced Coagulopathy: Complexities and Treatment Challenges in Intracranial Hemorrhage.
Document Type
Article
Source
Annals of Neurosciences. Jan2024, Vol. 31 Issue 1, p7-9. 3p.
Subject
*INTRACRANIAL hemorrhage
*PHYSICIANS
*BLOOD coagulation disorders
*CEREBRAL malaria
*VON Willebrand disease
*BLOOD coagulation factors
*INTRACRANIAL pressure
Language
ISSN
0972-7531
Abstract
This article discusses the complexities and treatment challenges of intracranial hemorrhage caused by malaria-induced coagulopathy. Malaria-induced coagulopathy can disrupt the body's normal clotting mechanism, leading to abnormal bleeding, including intracranial hemorrhage. The exact mechanisms underlying the development of intracranial bleeding in these cases are not fully understood, but it is believed to involve a combination of factors such as endothelial dysfunction, platelet dysfunction, and microvascular sequestration of infected erythrocytes. The management of intracranial hemorrhage associated with malaria-induced coagulopathy presents significant challenges, and further research is needed for better understanding and improved treatment strategies. [Extracted from the article]