학술논문

Fulminant inflammatory demyelination presenting as stroke‐in‐evolution in an elderly subject.
Document Type
Article
Source
Brain & Behavior. Aug2021, Vol. 11 Issue 8, p1-5. 5p.
Subject
*DEMYELINATION
*OLDER people
*STROKE
*OLDER patients
*SYMPTOMS
*DIAGNOSIS
Language
ISSN
2162-3279
Abstract
Background: Fulminant inflammatory demyelination is a possible presentation of inflammatory demyelinating disorders, thus representing a potential stroke mimic especially in younger patients. Aims of the study: To describe clinical and diagnostic pitfalls in a case of fulminant inflammatory demyelination presenting with stroke‐like symptoms in an elderly patient. Methods: Case report and case‐based review of the literature. Results: A 67‐year‐old woman, who accessed the emergency room as suspect stroke for hyperacute onset of rapidly worsening speech impairment and drowsiness, was later diagnosed with a huge brain inflammatory demyelination. Clinical, laboratory, and neuroimaging tests did not allow to put a more specific diagnosis. Due to the rapidly deteriorating course, she received immunosuppression with benefit. Conclusion: This report is meant to highlight the diagnostic challenges connected with fulminant inflammatory demyelination, which sometime can resemble a stroke‐in evolution and appear clinically unfitting for inclusion in any specific pathological entities within the broad‐spectrum of inflammatory demyelinating disorders. [ABSTRACT FROM AUTHOR]