부산대학교 도서관

Although there are controversies about the effectiveness of the treatment of CRAO, the AHA guidelines[[4]] recommend intravenous fibrinolysis as the first line of treatment and in cases where the latter is contraindicated, management with intra-arterial fibrinolysis is recommended. Keywords: Alteplase; central retinal artery occlusion; fibrinolysis; thrombolysis EN Alteplase central retinal artery occlusion fibrinolysis thrombolysis 2695 2697 3 07/15/22 20220701 NES 220701 Central retinal artery occlusion (CRAO) represents an ophthalmologic emergency given its repercussion on patient's final visual acuity (>90% retain a permanent loss of visual function).[[1]] Its incidence may be underestimated given that reports are mostly done in III level hospitals or higher, estimated at 8.5 per 100,000 people.[[2]] The risk of bilateral presentation is still uncommon, and is approximately 1-2% of the cases.[[2]] Medical evidence regarding the effectiveness of fibrinolytic therapy versus noninvasive therapy is still a debate due to controversial results. [Extracted from the article]