학술논문
AUF‐1 and skin inflammation: Atopic dermatitis and psoriasis.
Document Type
Article
Author
Source
Subject
*SKIN inflammation
*ATOPIC dermatitis
*PSORIASIS
*HUMAN cell culture
*SKIN biopsy
*ECZEMA
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Language
ISSN
0926-9959
Abstract
This article explores the role of AU-binding factor 1 (AUF-1) in chronic inflammatory skin conditions such as atopic dermatitis (AD) and psoriasis. The study examines the expression of AUF-1 in skin biopsies of AD and psoriasis patients and investigates the modulation of AUF-1 in vitro using human keratinocyte cell cultures. The results show a different pattern of AUF-1 expression in AD compared to psoriasis, suggesting a potential role of AUF-1 in chronic immune-driven skin inflammation. The findings highlight the importance of understanding endogenous mechanisms involved in resolving AD and identifying new therapeutic targets. [Extracted from the article]