학술논문

Choroid Plexus Carcinoma with Hyaline Globules: An Uncommon Histological Finding.
Document Type
Case Study
Source
Fetal & Pediatric Pathology. Jun2022, Vol. 41 Issue 3, p464-467. 4p.
Subject
*CHOROID plexus
*CARCINOMA
*AMYLASES
*ALPHA fetoproteins
CENTRAL nervous system tumors
Language
ISSN
1551-3815
Abstract
Background: Choroid plexus carcinoma (CPC) is a predominately pediatric CNS tumor with a variety of histologic features, with hyaline globules only reported once previously. Case report: A two-year-old male child presented with headaches, vomiting, and lower limb weakness. Radiological examination revealed a right temporoparietal intra-axial tumor. On histology, it showed features of CPC containing multiple eosinophilic intracytoplasmic and extracellular hyaline globular structures, which were PAS-positive, diastase resistant, and immunoreactive for alpha-fetoprotein (AFP). Conclusion: CPC can occasionally show AFP immune-positive hyaline globules. [ABSTRACT FROM AUTHOR]