학술논문

Telomeres: Not All Breaks Are Equal
Document Type
Article
Source
Current Biology. Aug2004, Vol. 14 Issue 15, pR613-R614. 0p.
Subject
*DNA
*DEOXYRIBOSE
*GENES
*PROTEINS
Language
ISSN
0960-9822
Abstract
ATM, Rad50 and Mre11 have been shown to prevent telomere fusion in Drosophila, thereby extending the protective role of DNA damage checkpoint proteins to non-canonical telomeres formed without telomerase. How do these proteins help chromosomal termini escape fusion through ‘repair’ while promoting repair of induced DNA breaks? [Copyright &y& Elsevier]