학술논문
Risk of leukaemia and residential exposure to air pollution in an industrial area in Northern Italy: a case-control study.
Document Type
Article
Author
Source
Subject
*LEUKEMIA risk factors
*MANUFACTURING industries
*AIR pollution
*CONFIDENCE intervals
*FOSSIL fuels
*HYDROCARBONS
*INORGANIC compounds
*INTERVIEWING
*PESTICIDES
*POWER plants
*PROBABILITY theory
*QUESTIONNAIRES
*RADIATION
*OCCUPATIONAL hazards
*ENVIRONMENTAL exposure
*MULTIPLE regression analysis
*CASE-control method
*DATA analysis software
*DESCRIPTIVE statistics
*CONFOUNDING variables
*ODDS ratio
*MANN Whitney U Test
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Language
ISSN
0960-3123
Abstract
Leukaemia risk in adult populations exposed to environmental air pollution is poorly investigated. We have carried out a population-based case-control study in an area that included a fossil fuel power plant, a coke oven and two big chemical industries. Information on residential history and several risk factors for leukaemia was obtained from 164 cases, diagnosed between 2002 and 2005, and 279 controls. A higher risk for subjects residing in polluted areas was observed, but statistical significance was not reached (adjusted OR = 1.11 and 1.56 for subjects living in moderately and in heavily polluted zones, respectively,p = 0.190). Results suggest a possible aetiological role of residential air pollution from industrial sites on the risk of developing leukaemia in adult populations. However, the proportion of eligible subjects excluded from the study and the lack of any measure of air pollution prevent definitive conclusions from being drawn. [ABSTRACT FROM PUBLISHER]