학술논문

Analytics of Quinine and its Derivatives.
Document Type
Article
Source
Critical Reviews in Analytical Chemistry. 2016, Vol. 46 Issue 2, p139-145. 7p.
Subject
*QUINIDINE
*QUININE
*CHEMICAL derivatives
*BIOSYNTHESIS
*MALARIA treatment
*HIGH performance liquid chromatography
*CAPILLARY electrophoresis
*THERAPEUTICS
Language
ISSN
1040-8347
Abstract
The objective of this study was to perform a synthesis and analysis of the most important information on quinine and its derivatives, which are still very important in the treatment of malaria. The analysis of stereoisomers of quinine and its derivatives was conducted using two techniques, high-performance liquid chromatography and capillary electrophoresis. Particularly noteworthy is the technique used for the determination of isotachophoresis, referred to as one of the so-called green chemistry techniques. Particular attention was paid to properties and the use of quinine and its derivatives in the treatment of malaria. The analytical part will supplement knowledge about quinidine, quinine, and cinchonidine, and will contribute to the growth of research on the so-much-needed drugs against malaria. [ABSTRACT FROM PUBLISHER]