학술논문
Tumor-specific cytolytic CD4 T cells mediate immunity against human cancer.
Document Type
Article
Author
Cachot, Amélie; Bilous, Mariia; Yen-Cheng Liu; Xiaokang Li; Saillard, Margaux; Cenerenti, Mara; Rockinger, Georg Alexander; Wyss, Tania; Guillaume, Philippe; Schmidt, Julien; Genolet, Raphaël; Ercolano, Giuseppe; Protti, Maria Pia; Reith, Walter; Ioannidou, Kalliopi; de Leval, Laurence; Trapani, Joseph A.; Coukos, George; Harari, Alexandre; Speiser, Daniel E.
Source
Subject
*CYTOTOXIC T cells
*PERFORINS
*GRANZYMES
*NEURAL cell adhesion molecule
*PROGRAMMED cell death 1 receptors
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Language
ISSN
2375-2548
Abstract
The article offers information on a study that explores how tumor-specific cytolytic CD4 T cells mediate immunity against human cancer. It mentions about the enhanced cytotoxicity of tumor-specific CD4 T cells, suggesting that targeting these cells might prove synergistic with other cancer immunotherapies.